Publications by authors named "Francois Belle Moudourou"

Article Synopsis
  • Hymenoptera venom allergy significantly affects quality of life, and while allergen immunotherapy (AIT) is effective, predicting its success remains challenging due to a lack of biomarkers.
  • This study analyzed patient data from 1985 to 2022 at the University Hospital of Limoges to assess the role of IgE blocking activity as a potential predictor of AIT efficacy against Hymenoptera venom.
  • Results indicated that IgE blocking activity did not predict relapse after stopping AIT, but a correlation was found between this activity and IgG antibody levels, suggesting that further research is needed to explore the role of these antibodies in monitoring treatment outcomes.
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Background: A major problem of venom-specific immunotherapy (VIT) is the absence of reliable parameters for deciding treatment discontinuation.

Aim Of The Study: Intracutaneous tests (ICTs), the basophil activation test (BAT), specific IgEs (sIgEs) and blocking factor (BF) activity were measured during VIT. We made an evaluation by means of a protective index (PI) including ICT, BAT and BF values.

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