Metabolism of hibernating myocardium assessed by microdialysis during surgical revascularization: report of a case.

We present an 80-year-old woman with hibernating myocardium in the left anterior descending coronary artery (LAD) territory who underwent surgical revascularization and metabolic evaluation of the dysfunctioning segments by microdialysis (microD) technique. Myocardial lactate, pyruvate, and glucose did not show obvious changes throughout the procedure. Conversely, myocardial glycerol and glutamate concentrations markedly increased early after cardioplegic arrest and subsided after weaning from cardiopulmonary bypass (CPB) and recovery of myocardial function.

N-acetylcysteine for prevention of acute renal failure in patients with chronic renal insufficiency undergoing cardiac surgery: a prospective, randomized, clinical trial.

Objective: To assess the preventive effect of the antioxidant N-acetylcysteine on postoperative acute renal failure in patients with renal insufficiency undergoing cardiac surgery.

Design: Randomized, placebo-controlled, prospective study.

Setting: University cardiology center.

Long-term outcome of survivors of prolonged intensive care treatment after cardiac surgery.

Background: The relative impact of perioperative risk profile and postoperative complications on long-term outcome in cardiac surgical patients is currently unclear. The aim of this work was to assess the relative predictive value of the European System for Cardiac Operative Risk Evaluation (EuroSCORE) and Sequential Organ Failure Assessment (SOFA) on long-term event-free survival in this patient population.

Methods: Preoperative and postoperative variables, EuroSCORE and SOFA, 30-day mortality, and long-term mortality or hospital admission for cardiovascular events were assessed in 115 consecutive cardiac surgical patients in whom multiorgan dysfunction syndrome developed postoperatively.

Sudden heart failure due to a ruptured posterior Valsalva sinus aneurysm into the right atrium: feasibility of catheter closure using the Amplatzer duct occluder.

Valsalva sinus aneurysms are usually congenital and relatively rare and tend to be more frequent in adults. Rupture of these aneurysms can result in sudden death or in an abrupt and rapid progressive heart failure. Surgical repair is the traditional treatment of choice.

Myocardial lactate metabolism in relation to preoperative regional wall motion and to early functional recovery after coronary revascularization.

Objective: To evaluate myocardial lactate metabolism as a marker of functional status after surgical coronary revascularization.

Design: Single-center, prospective, cohort study.

Setting: Tertiary care teaching hospital.

Application of the sequential organ failure assessment score to cardiac surgical patients.

Objective: To assess the applicability of the sequential organ failure assessment (SOFA) score to cardiac surgical patients.

Design: Observational cohort study.

Setting: Adult cardiac surgical ICU.