Association of retinal detachment with age 50 years or younger at onset in patients with acute retinal necrosis.

Background: Due to the guarded prognosis of acute retinal necrosis (ARN), it is relevant to develop a strategy to early categorize those patients in a higher risk of worse outcomes. The purpose of this study is to describe clinical features and predictive factors for retinal detachment (RD) in patients with ARN.

Methods: Retrospective observational case series of 34 adult patients (38 eyes) with ARN examined between January 2005 and July 2015 in the National Eye Institute (Bethesda, USA), the Department of Ophthalmology, University of Chile (Santiago, Chile), and APEC (CDMX, Mexico).

[Plastic beauty, eugenics and physical education in Chile: a commentary on the work "Characteristics of physical education", by Luis Bisquertt (1930)].

The article seeks to introduce and contextualize the work "Characteristics of physical education" ("Aspectos de la educación física"), by Luis Bisquertt, which emphasizes the effort to ameliorate racial aspects in Chile, in 1930, thru physical education eugenics, whose body paradigm were the Hellenic classical statues. One of the key concepts of this document is plastic beauty, whose meaning overlaps with the idea of normality and sanity, creating pathologies on those bodies that were considered outside of the athletic standards, a situation that was aggravated by the sedentary conditions of modern times.

Diabetes Mellitus-Associated Uveitis: Clinical Features in a Chilean Series.

Purpose: To describe clinical features of patients with diabetes mellitus-associated uveitis (DMAU).

Methods: Retrospective analysis of clinical records of patients with uveitis and diabetes mellitus (DM) presented in an uveitis referral centre in Chile. Demographic data, comorbidities, complete ophthalmic examination, and treatments were analyzed.

Mycophenolate Mofetil Therapy in Refractory Inflammatory Eye Disease.

Purpose: To study the efficacy and incidence of treatment-related side effects of mycophenolate mofetil (MMF) therapy in patients with noninfectious inflammatory eye diseases.

Methods: Retrospective cohort study of 27 Chilean patients treated for noninfectious inflammatory eye diseases using MMF therapy over a 10-year period. Main outcome measures were: ability to control ocular inflammation and to taper prednisone to ≤10 mg daily (treatment success); incidence of treatment-related side effects.

Comparison of the clinical efficacy of two different immunosuppressive regimens in patients with chronic vogt-koyanagi-harada disease.

Purpose: To prospectively compare 2 immunosupressive regimens in patients with active Vogt-Koyanagi-Harada disease in spite of systemic glucocorticoid treatment.

Methods: Forty-four patients were diagnosed between 1998 and 2005. Twenty-one developed chronic intraocular inflammation in spite of glucocorticoid treatment and were randomized to receive either prednisone and azathioprine (AZA) (n = 12) or prednisone and cyclosporine (CyA) (n = 9).

[Retrospective review of 44 Chilean patients with Behçet disease].

Background: Behçet's disease (BD) is a rare multisystemic inflammatory disease that is potentially disabling and may cause death.

Aim: To describe the characteristics of BD patients from two Chilean centers.

Patients And Method: Retrospective review of the clinical records of patients with BD attended in two rheumatology services between 1985 and 2007.

[Role of Azathioprine in steroid resistant non infectious ocular inflammatory diseases].

Background: Topical and systemic steroids are the first line of treatment of non infectious inflammatory ocular disease. Immunosuppresants are reserved as a second line treatment.

Aim: To evaluate the role of Azathioprine (AZA) as a coadyuvant immunosuppressive treatment for non infectious ocular inflammatory diseases (OIDs) resistant to systemic steroid therapy in a retrospective, noncomparative interventional case series.

[Effectiveness of infliximab in patients with Behçet syndrome and severe uveoretinitis. Report of five cases].

The efficacy and safety of repeated administration of infliximab was evaluated in five patients (two men, three women) with Behçet syndrome accompanied by severe uveoretinitis. Ocular and extra ocular inflammation was suppressed in all patients during the observation period without any serious adverse reactions. The results in these patients suggests that TNF-á blockade is effective in patients with severe ocular Behçet syndrome.

[Carotid cavernous fistula: the importance of its opportune diagnosis and treatment to prevent blindness].

A carotid cavernous fistula is an abnormal communication between a branch of the carotid artery and the cavernous sinus generating an arteriovenous fistula that can cause severe ocular damage. We hereby report two cases of carotid cavernous fistulas. A 69-year-old male with a 2-month history of right eyelid swelling and red eye aggrarated by diplopia, exophthalmus, and limitation of ocular movements one week before consulting.