Publications by authors named "Francisco Vaz Guimaraes Filho"

Background: Aspergillosis is caused by fungi from the species, mainly . Patients with aspergillosis typically have an underlying immunosuppression, and it is rare within the central nervous system (CNS) in an immunocompetent host. The mortality rate is as high as 90% if untreated, and the diagnosis is usually delayed due to nonspecific clinical presentation.

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Background: Cavernous sinus (CS) tumors often are considered inoperable. We present our experience with endoscopic endonasal surgery (EES) and compare the outcomes for different tumor.

Methods: EES (medial or lateral approach) was used in 234 patients with CS tumors.

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Objective: Transpetrosal approaches for the treatment of petroclival meningiomas are often associated with substantial morbidity and long recovery. With the goal of early clinical improvement, we have used less invasive surgical approaches for petroclival meningiomas.

Methods: We retrospectively reviewed 32 patients with petroclival meningiomas.

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Article Synopsis
  • - The study compares two surgical approaches—endoscopic endonasal (EEA) and bifrontal craniotomy (BFC)—for treating olfactory groove meningiomas, focusing on outcomes and MRI changes post-surgery.
  • - A total of 70 patients were examined, and after matching 10 pairs based on tumor volumes and timing of scans, key outcomes like cerebrospinal fluid leaks and resection rates were analyzed, showing similar overall results.
  • - Notably, EEA showed significantly less postoperative FLAIR signal change in the frontal lobe compared to BFC, suggesting EEA may result in better postoperative MRI outcomes.
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Background: Oncologic outcomes for sinonasal and skull base squamous cell carcinoma (SCC) treated with an endoscopic endonasal approach (EEA) needs investigation.

Methods: Patients with SCC treated with EEA were stratified by treatment strategy and tumor etiology and reviewed.

Results: Thirty-four patients were treated with EEA, or which 27 had definitive resection and 7 had debulking surgery.

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Article Synopsis
  • Transclival endoscopic endonasal surgery (EES) is used to treat posterior fossa tumors, but the best way to reconstruct large clival defects post-surgery is still unclear.
  • A study compared postoperative anatomical changes in 103 patients who underwent EES with normal individuals and similar cases with preserved anatomy, revealing a notable anterior displacement of the pons in 14 patients (13.6%).
  • Significant findings included changes in the pons and fourth ventricle dimensions, with an association between higher body mass index (BMI) and the severity of these changes.
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Objective: Unilateral hydrocephalus (UH) is characterized by enlargement of just one lateral ventricle. In this paper, the authors will demonstrate their experiences in the neuroendoscopic management of this uncommon type of hydrocephalus.

Method: The authors retrospectively reviewed a series of almost 800 neuroendoscopic procedures performed from September 1995 to July 2010 and selected seven adult patients with UH.

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Object: Ideal surgical training models should be entirely reliable, atoxic, easy to handle, and, if possible, low cost. All available models have their advantages and disadvantages. The choice of one or another will depend on the type of surgery to be performed.

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