Endoscopic treatment of biliary complications after liver transplantation.

Background: biliary complications are an important cause of morbidity and mortality after liver transplantation. Endoscopic retrograde cholangiopancreatography (ERCP) is a therapeutic option, which is less invasive than surgical management.

Materials And Methods: the endoscopic management with ERCP of patients with biliary complications after liver transplantation in the Complexo Hospitalario Universitario de A Coruña between 2012 and 2018 was reviewed.

Effectiveness and safety of sofosbuvir/velpatasvir ± ribavirin vs glecaprevir/pibrentasvir in genotype 3 hepatitis C virus infected patients.

Objectives: Sofosbuvir/velpatasvir±ribavirin (SOF/VEL±RBV) and glecaprevir/pibrentasvir (GLE/PIB) are the drug combinations of choice for treating individuals with genotype 3 hepatitis C virus (G3-HCV) infection. The objective of this study was to evaluate the effectiveness and safety of SOF/VEL±RBV compared with GLE/PIB for treating G3-HCV infection under routine clinical practice conditions.

Methods: We conducted a prospective observational cohort study of individuals with G3-HCV infection who initiated treatment with SOF/VEL +/-RBV or GLE/PIB between April 2017 and July 2018.

Effectiveness and safety of direct-acting antivirals in hepatitis C infected patients with mental disorders: Results in real clinical practice.

The aim of this study is to analyze the effectiveness and safety of direct-acting antivirals (DAAs) in psychiatric patients with chronic hepatitis C (CHC). Secondary objectives included adherence and drug-drug interaction (DDIs) evaluations. Prospective observational comparative study carried out during 3 years.

Nomogram and Validity of a Model for Predicting Malnutrition in Patients on Liver Transplant Lists.

Background: Malnutrition is associated with increased morbimortality in liver transplant patients, and it is important to identify factors related to nutritional status in these patients.

Aims: Determine variables associated with malnutrition and create a nomogram in liver transplant candidates.

Methods: Cross-sectional study (n = 110).

Concordance among methods of nutritional assessment in patients included on the waiting list for liver transplantation.

Background: The aim of the present study was to determine the extent of malnutrition in patients waiting for a liver transplant. The agreement among the methods of nutritional assessment and their diagnostic validity were evaluated.

Methods: Patients on the waiting list for liver transplantation (n = 110) were studied.

Assessment of nutritional status and health-related quality of life before and after liver transplantation.

Background: Patients with chronic liver disease frequently suffer from malnutrition, together with a decline in their health-related quality of life. This study was carried out with the aim of evaluating the nutritional status, complications of medical and surgical care, anxiety, health-related quality of life and dependence level on basic and instrumental activities of daily living in pre- and post-liver transplant patients.

Methods/design: A prospective observational study with follow-up of patients on the waiting list for liver transplants who subsequently received a transplant at the University Hospital Complex in A Coruña during the period 2012-2014 (n = 110).

[Risk factors associated with invasive fungal infection in orthotopic liver transplantation].

Background And Objective: Invasive fungal infection (IFI) in orthotopic liver transplantation (OLT) influences survival, hence the need for risk predictors. We have determined the incidence and risk factors associated with invasive fungal infection in OLT.

Patients And Method: 165 OLTs performed in 152 receptors from May 1994 to May 1998 at the Hospital Juan Canalejo (La Coruña), were included in the study.