[Dieulafoy's lesion of the gallbladder as a cause of hemobilia with hemoperitoneum].

Dieulafoy's lesion is an uncommon vascular anomaly causing massive gastrointestinal hemorrhage, characterized by bleeding from an arteriole that protrudes through a tiny mucosal defect. Although Dieulafoy's lesion was initially described in the stomach and upper gastrointestinal tract, cases have also been reported in the colon, rectum and anal canal. We report the first case of Dieulafoy's lesion in the gallbladder, which presented as massive peritoneal bleeding.

Molecular diagnosis of sentinel lymph nodes for breast cancer: one step ahead for standardization.

Sentinel node (SN) pathologic analysis shows great limitations related to reproducibility and challenges pathologists with respect to methodology and standardization. Recently, a new, highly specific and sensitive molecular procedure has been developed, based on cytokeratin 19 messenger RNA amplification, which allows for fast and effective intraoperative evaluation of the SN. Our aim in this study was to compare 2 arms for intraoperative evaluation: one study arm with 478 cases in which an exhaustive histopathologic procedure was performed and the other study arm with 211 cases that were analyzed using the new molecular method.

[Atypical or bizarre leiomyoma of the scrotum. Report of one case and bibliographic review].

Objectives: To describe the clinicopathological characteristics of the scrotal bizarre leiomyoma in order to increase our understanding, and avoid the possibility of erroneous diagnosis and treatment.

Results: We report the case of a 43 year-old patient with a pendulous nodular scrotal tumour, which after microscopic study could be seen to be of smooth muscular origin, corresponding, because of its peculiar histological characteristics, to the rare variety called atypical or symplasmic bizarre leiomyoma.

Conclusion: Although it is a form of leiomyoma which is extremely infrequently found in the scrotum, it is necessary to know it can occur and to know that we are dealing with a benign tumour that should be treated as such.