Publications by authors named "Francisco Pastor-Sifuentes"

Purpose: The Memorial Sloan Kattering Frailty Index (MSK-FI) and the Skeletal Muscle Index (SMI) have recently gained attention as markers of frailty and decreased physiologic reserve, and are promising as predictors of adverse postoperative outcomes in patients undergoing oncologic surgery. The objective of this study was to establish the prognostic accuracy of these indexes in a cohort of patients with colorectal cancer subjected to surgical intervention.

Methods: We performed an observational study including all patients older than 60 years, subjected to colorectal cancer surgery between January 2010 and May 2020, and stratified our cohort based on the presence of frailty, as defined by MSK-FI ≥ 3.

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Retrospective impact evaluation of frailty as measured by the Memorial Sloan Kettering Frailty Index (MSK-FI) on outcomes in older women surgically treated for advanced epithelial ovarian cancer (EOC). Women ≥ 60 years with stage IIIC/IV EOC who underwent primary debulking surgery (PDS) or interval debulking surgery (IDS) were included. Medical records were reviewed for patients' characteristics and outcomes.

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Background: Breast conservative surgery (BCS) is an adequate treatment for patients with early breast cancer. Local recurrence is associated with diverse factors. Our objective was to evaluate risk factors associated with finding residual tumor in patients with positive margins in BCS.

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Article Synopsis
  • The study focused on the increasing number of frail older adults undergoing major abdominal surgeries and evaluated the modified Rockwood frailty index (mRFI) as a tool for predicting postoperative complications and mortality.
  • It analyzed data from 140 patients aged over 65 and found that frail patients (mRFI >0.25) experienced longer hospital stays, higher rates of ICU admissions, readmissions, and increased mortality rates compared to non-frail patients.
  • The analysis revealed that frailty was a significant independent predictor of postoperative complications, with the mRFI showing moderate sensitivity and specificity as a predictive tool for complications and ICU admissions.
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Article Synopsis
  • Gastrointestinal schwannomas are benign tumors primarily found in the stomach, making surgery the preferred treatment method, often involving laparoscopic approaches.
  • The main differential diagnosis for gastric schwannomas is gastrointestinal stromal tumors (GISTs), while esophageal schwannomas are rarer and often confused with leiomyomas.
  • A systematic review indicated that gastric schwannomas have a high prevalence, with long-term disease-free survival rates over 36 months post-surgery, suggesting effective curative outcomes.
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Due the shortage of organ donors and the increase in the waiting list of kidney transplant recipients (KTR), alternative strategies have been considered with the aim of increasing the number of organs available. The use of kidneys from donors with acute renal failure and elevated serum creatinine has been considered as a way to increase the number of donors. The objective of this work is to report the 3-year follow-up of three KTR patients of a deceased donor with serum creatinine greater than or equal to 5 mg/dL.

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