Publications by authors named "Francisco Ortega-Santana"

Purpose: To report a case and management of persistent hypotony with hypotony-induced maculopathy after CyPass device implant.

Background: The CyPass was the first supraciliary device approved by FDA and commercially available. Efficacy studies showed adequate intraocular pressure (IOP)-lowering results in combination with phacoemulsification.

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Objective: The subcutaneous venous network (SVN) is difficult to see with the naked eye. Near infrared illumination (NIr-I) claims to improve this. The aims of this observational study were to investigate whether there are differences between the different methods; to quantify the length and diameter of SVNs; and to confirm if they differ between C and C CEAP limbs.

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Background And Objective: The elastic fibres are an essential component of the extracellular matrix in blood vessel walls that allows a long-range of deformability and passive recoil without energy input. The quantitative determination of elastic fibres will provide information on the state of the vascular wall and to determine the role and behaviour of this key structural element in different physiological and pathological vascular processes.

Methods: We present a segmentation method to identify and quantify elastic fibres based on a local threshold technique and some morphological characteristics measured on the segmented objects that facilitate the discrimination between elastic fibres and other image components.

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Purpose: To develop a digital image processing method to quantify structural components (smooth muscle fibers and extracellular matrix) in the vessel wall stained with Masson's trichrome, and a statistical method suitable for small sample sizes to analyze the results previously obtained.

Methods: The quantification method comprises two stages. The pre-processing stage improves tissue image appearance and the vessel wall area is delimited.

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