Publications by authors named "Francisco Monteon"

Background: Tumoral calcinosis is an autosomal recessive disorder characterized by ectopic calcification and hyperphosphatemia.

Methods: We describe a family with tumoral calcinosis requiring amputations. The predominant metabolic anomaly identified in three affected family members was hyperphosphatemia.

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Introduction: In Mexico, CAPD survival has been analyzed in few studies from the center of the country. However, there are concerns that such results may not represent what occurs in other province centers of our country, particularly in our geographical area.

Aim: To evaluate the patient and technique survival on CAPD of a single center of the west of Mexico, and compare them with other reported series.

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Article Synopsis
  • Drug-related hepatotoxicity is prevalent among renal transplant recipients with chronic liver disease due to impaired drug metabolism.
  • A case study of a 26-year-old male, who has survived 30 years post-renal transplant, highlights the risks of medications like azathioprine and pravastatin leading to liver damage.
  • The importance of cautious use and monitoring of hepatotoxic drugs in these patients is emphasized, especially those with chronic hepatitis C virus infections.
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Background And Aim: To what extent the serum levels of alanine aminotransferase (ALT) are related to histological characteristics of liver damage caused by hepatitis C virus (HCV) infection among patients with end-stage renal disease (ESRD) remains unclear.

Methods: Patients with a positive anti-HCV antibody titer confirmed by supplemental tests were evaluated by liver biopsy. We compared ALT levels in patients with and without renal damage, with similar histological grades and stages of inflammation and fibrosis.

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  • The study investigates the incidence and risk factors of posttransplant diabetes mellitus (PTDM) in Mexican kidney transplant recipients, finding a 10.1% occurrence among the 522 participants.
  • Key independent risk factors for developing PTDM included a cumulative prednisone dosage greater than 13 grams and experiencing one or more acute rejection episodes post-transplantation.
  • The findings suggest a need for further research into how inflammatory mechanisms related to acute rejection may contribute to the development of PTDM.
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Background: Patients with high peritoneal permeability have the greatest degree of inflammation on continuous ambulatory peritoneal dialysis (CAPD), which may be associated with their higher mortality. Nocturnal intermittent peritoneal dialysis (NIPD; "dry day") may decrease inflammation by reducing the contact between dialysate and peritoneum and/or providing better fluid overload control. Therefore, the aims of this study were to determine and compare serum and dialysate concentrations of C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor alpha (TNF-alpha) of patients with high or high-average peritoneal transport on CAPD, changed to NIPD, and ultimately to continuous cyclic peritoneal dialysis (CCPD).

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A total of 1,356 kidney transplants has been performed in the Hospital de Especialidades del Centro Médico Nacional de Occidente, IMSS, in Guadalajara Mexico, including 935 in the past 8 years. This represents an important increase of this activity in our country. Of the total transplants, 1,218 (90%) were from living donors and only 138 (10%) were from cadaveric donors, a number that we hope to increase.

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Article Synopsis
  • The study investigates the risk factors for renal graft loss in Mexico and Latin America, focusing on patients who received their first kidney transplants between 1976 and 1999.
  • A total of 326 patients were analyzed, with key findings indicating that acute rejection episodes and lower HLA haplotype matching significantly predicted graft loss.
  • Overall, while graft survival rates were similar to those in developed countries, the main risks identified for long-term failure were acute rejection and HLA mismatching.
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