Dysregulation in the microbiota by HBV and HCV infection induces an altered cytokine profile in the pathobiome of infection.

Viral hepatitis is a public health problem, about 1 million people die due to complications of this viral disease, the etiological agents responsible for inducing cirrhosis and cellular hepatocarcinoma are HBV and HCV, both hepatotropic viruses that cause asymptomatic infection in most cases. The regulation of the microbiota performs many physiological functions, which can induce normal intestinal function and produce essential nutrients for the human body. Metabolites derived from gut microbiota or direct regulation of host immunity and metabolism have been reported to profoundly affect tumorigenesis in liver disease.

Filling the gaps on parasites of : Helminth community structure of (Anura: Hylidae) from the Brazilian Amazon.

is an arboreal anuran widely distributed in South America. However, there are no parasitological studies conducted on the species, resulting in a parasite fauna completely unknown. Thus, this study aims to characterize the parasitic community structure of in the municipality of Pedra Branca do Amapari, Amapá state, Amazon region, Brazil.

Two names, one species: redescription and phylogenetic position of Freitas, 1959 provides new insights into the evolutionary history of the Cosmocercidae.

are gastrointestinal parasites of anurans, distributed throughout Central and South America. and are some of the most commonly reported species parasitising anurans from Brazil, and the morphological differences between them are unclear. In the present study, we redescribed based on a re-examination of type series and newly collected material from the frog in the state of Amapá, Brazil.

n. gen., n. sp. (Nematoda: Cosmocercoidea: Atractidae) parasite of yellow-spotted Amazon river turtle, Troschel (Testudines: Podocnemididae) in Brazilian Amazon.

Nematodes collected from the stomach of the yellow-spotted turtle Troschel, 1848 (Testudinidae) in the Brazilian state of Pará are assigned to a new genus, allocated to the family Atractidae (Cosmocerdoidea). n. gen.

Rosmarinic acid turned α-syn oligomers into non-toxic species preserving microtubules in Raw 264.7 cells.

Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder worldwide, and the therapeutic is focused on several approaches including the inhibition of fibril formation by small compounds, avoiding the formation of cytotoxic oligomers. Thus, we decided to explore the capacity of compounds carrying catechol moieties to inhibit the progression of α-synuclein. Overall, the compounds rosmarinic acid (1), carnosic acid (2), carnosol (3), epiisorosmanol (4), and rosmanol (5) avoid the progression of fibril formation assessed by Thiofavine T (ThT), and atomic force microscopy images showed that morphology is influenced for the actions of compounds over fibrillization.

Mechanical force activates the light-dependent channels TRP and TRPL in excised patches from the rhabdomere of Drosophila photoreceptors.

Drosophila phototransduction in light-sensitive microvilli involves a metabotropic signaling cascade. Photoisomerized rhodopsin couples to G-protein, activating phospholipase C, which cleaves phosphatidylinositol bisphosphate (PIP2) into inositol trisphosphate, diacylglycerol (DAG) and a proton. DAG is converted into phosphatidic acid by DAG-kinase and metabolized to L-linoleoyl glycerol (2-LG) by DAG-lipase.

Correction: Photoluminescence modification of europium(III)-doped MAlO (M = Zn, Mg) spinels induced by Ag@SiO core-shell nanoparticles.

Correction for 'Photoluminescence modification of europium(III)-doped MAlO (M = Zn, Mg) spinels induced by Ag@SiO core-shell nanoparticles' by Rodrigo A. Valenzuela-Fernández , , 2024, https://doi.org/10.

HOTSPOT: An ad hoc teamwork platform for mixed human-robot teams.

Ad hoc teamwork is a research topic in multi-agent systems whereby an agent (the "ad hoc agent") must successfully collaborate with a set of unknown agents (the "teammates") without any prior coordination or communication protocol. However, research in ad hoc teamwork is predominantly focused on agent-only teams, but not on agent-human teams, which we believe is an exciting research avenue and has enormous application potential in human-robot teams. This paper will tap into this potential by proposing HOTSPOT, the first framework for ad hoc teamwork in human-robot teams.

Photoluminescence modification of europium(III)-doped MAlO (M = Zn, Mg) spinels induced by Ag@SiO core-shell nanoparticles.

In recent years, there has been an increasing interest in developing new inorganic compounds with exceptional properties for advanced materials. Specifically, compounds containing europium have attracted much attention due to their luminescent properties. These compounds are used in electronics, biotechnology, medicine, and catalysis.

Structural Characterization and Magnetic Behavior Due to the Cationic Substitution of Lanthanides on Ferrite Nanoparticles.

A new series of [FeLn]O nanoparticles, with Ln = Gd; Dy; Lu and = 0.05; 0.1; 0.

n. sp. (Eucestoda: Proteocephalidae), a parasite of (Linnaeus, 1758), with redescription of (Santos and Rolas, 1973) from the Brazilian Amazon.

is the most diverse genus among proteocephalids, composed of species commonly found parasitizing snakes worldwide. However, the diversity of in the Neotropical region is still underestimated. This study describes n.

Effect of Gelatin Coating and GO Incorporation on the Properties and Degradability of Electrospun PCL Scaffolds for Bone Tissue Regeneration.

Polymer-based nanocomposites such as polycaprolactone/graphene oxide (PCL/GO) have emerged as alternatives for bone tissue engineering (BTE) applications. The objective of this research was to investigate the impact of a gelatin (Gt) coating on the degradability and different properties of PCL nanofibrous scaffolds fabricated by an electrospinning technique with 1 and 2 wt% GO. Uniform PCL/GO fibers were obtained with a beadless structure and rough surface.

A New Species of Cosmocerca Diesing, 1861 (Nematoda: Cosmocercidae) in Elachistocleis haroi Pereyra, Akmentins, Laufer, and Vaira, 2013 (Amphibia: Microhylidae) from South American Chaco.

Purpose: Cosmocercids are common nematodes that parasitize the digestive tract and lungs of amphibians and reptiles around the world. They are commonly found in leptodactylid and bufonid anurans in South America, primarily in Brazil and Argentina. This paper describes a new species of genus Cosmocerca based on specimens collected in a microhylid from the Dry Chaco ecoregion.

Orientatractis bowseri n. sp. (Nematoda: Cosmocercoidea: Atractidae) parasite of Peltocephalus dumerilianus (Schweigger) (Testudines: Podocnemididae) from the Brazilian Amazon.

Peltocephalus dumerilianus (Schweigger) is a diurnal freshwater turtle widely distributed in the Orinoco and Amazon River basins in Brazil, Colombia, Peru, Ecuador, Venezuela, and French Guiana. During a helminthological survey of freshwater turtles from the Brazilian Amazon, numerous nematodes with characteristics of the genus Orientatractis Petter, 1966 were recovered from the stomach of Peltocephalus dumerilianus. These nematodes were different from all congeneric species, and we describe herein.

A new species of Aplectana Railliet & Henry, 1916 (Nematoda: Cosmocercidae) in the Brazilian Amazon and the taxonomic status of Aplectana longa.

Nematodes of the genus Aplectana Railliet & Henry, 1916 are common parasites of the digestive tract of amphibians and reptiles in the Neotropical region. During a parasite survey on Boana boans (Linnaeus, 1758), we found specimens of nematodes with Aplectana characteristics. We observed a set of characteristics that differs the species of our study from its congeners, and the present study describes a new species of Aplectana parasite of B.

Characterization of biofilm formation by strains in response to arsenic exposure.

In this work, we characterized the composition, structure, and functional potential for biofilm formation of strains isolated from the Salar de Huasco in Chile in the presence of arsenic, an abundant metalloid in the Salar that exists in different oxidation states. Our results showed that the strains tested exhibit a significant capacity to form biofilms when exposed to arsenic, which would contribute to their resistance to the metalloid. The results highlight the importance of biofilm formation and the presence of specific resistance mechanisms in the ability of microorganisms to survive and thrive under adverse conditions.

A new species of (Nematoda: Cosmocercoidea: Atractidae) parasite of Yellow-Spotted Amazon River Turtle, Troschel, 1848 (Testudines: Podocnemididae) in Brazilian Amazon.

The current study describes a new species of nematode, n. sp. (Atractidae), from the stomach and large intestine of Troschel, 1848 (Testudinidae), collected in the Tocantins and Xingu rivers in the Brazilian state of Pará.

α-Synuclein Drives Tau's Cytotoxic Aggregates Formation through Hydrophobic Interactions.

Tau and α-synuclein are proteins involved in pathologies known as tauopathies and synucleinopathies, respectively. Moreover, evidence shows that there is a crosstalk between them as is seen in the brains of individuals with sporadic neurodegenerative disorders. Based on that, we present data showing that the hydrophobic α-peptide VTGVTAVAQKTV induces the aggregation of the full-length tau fragment in the absence of heparin assessed by ThT.

New species of (Nematoda: Camallanidae) from the scorpion mud turtle (Testudines: Kinosternidae) from eastern Amazon, Brazil.

The genus Yeh, 1960 allocates parasitic nematodes of freshwater turtles distributed across the Oriental, Neotropical, and Palearctic regions. Five of 10 valid species of the genus occur in the Neotropical region, and three have been recorded parasitizing Linnaeus, 1766. In the present work, we describe a new species of , a gastrointestinal parasite of from the Brazilian Amazon, using light and scanning electron microscopy.

A Comparative Study of the Synthesis and Characterization of Biogenic Selenium Nanoparticles by Two Contrasting Endophytic Selenobacteria.

The present study examined the biosynthesis and characterization of selenium nanoparticles (SeNPs) using two contrasting endophytic selenobacteria, one Gram-positive ( sp. E5 identified as ) and one Gram-negative ( sp. EC5.

Dipeptidyl peptidase 4 (DPP4) in fecal samples: validation of the extraction methodology and stability in short-term storage conditions.

Objectives: This study assesses the clinical relevance of dipeptidyl peptidase 4 (DPP4) membrane exopeptidase as a biomarker of inflammatory bowel disease (IBD). A spike-and-recovery approach of DPP4 in fecal samples was used to compare two different methods for protein extraction, followed by a stability assessment.

Methods: Fecal samples of healthy volunteers spiked with known concentrations of recombinant DPP4 were processed using a standard manual extraction protocol and the CALEX protocol.

"Revisiting the past": a redescription of Physaloptera retusa (Nemata, Physalopteridae) from material deposited in museums and new material from Amazon lizards.

Physaloptera Rudolphi, 1819 is a genus of nematodes that includes approximately 100 species parasitic in vertebrates around the world. From these, approximately 30 occur in the Neotropical region, with nine reported from neotropical reptiles. Physaloptera spp.

Method for lineage typing of epidemic Renibacterium salmoninarum in Chilean salmon farms.

Renibacterium salmoninarum (Rs) is the etiological agent of bacterial kidney disease (BKD), which significantly affects farmed and wild salmonids worldwide. Although the whole genome of Rs (~3.1 million nucleotides) is highly conserved, genomic epidemiology analyses have identified four sub-lineages from Chilean isolates.

Morphological and molecular characterization of n. sp. (Nematoda: Cosmocercidae), parasitic in hylid frogs from the Brazilian Amazon.

Wilkie, 1930 are gastrointestinal parasites commonly found in amphibians and reptiles, with 4 species reported from the Neotropical region. In the present study, a new species of , namely n. sp.