Overexpression of MMP-3 and uPA with Diminished PAI-1 Related to Metastasis in Ductal Breast Cancer Patients Attending a Public Hospital in Mexico City.

Extracellular matrix metalloproteases and the fibrinolytic system are important protease systems interacting with each other in charge of remodeling and recycling of tissues. Their role in tumor invasion and metastasis is often discussed. In this study several metalloproteases such as MMP-1, MMP-3, MMP-9, and TIMP-1 together with molecules from the fibrinolytic system like uPA, its receptor uPAR, and its inhibitor, PAI-1, were studied by immune-histochemistry to establish a comparison with and without metastasis.

[Clear cell adenocarcinoma arising from abdominal wall endometriosis].

Background: Clear cell carcinoma originating in the abdominal wall is a rare event. It is generally associated with endometrial tissue implants left behind after a caesarean section or other gynaecological operations. Its pathophysiology is complex and controversial.

[Frequency of cancer in a specialty hospital in Mexico City. Implications for the development of early detection methods].

Background: Cancer is the second cause of death in Mexico. The Juarez Hospital of Mexico is a highly specialized general hospital in which the frequency of cancer treated at the Oncology Unit is a representative sample of the frequency of cancer in the country.

Objective: To learn about the frequency of presentation of tumors diagnosed in a third level hospital.

[Medullary carcinoma experience in breast oncology unit of Hospital Juarez Mexico].

Background: Medullary breast cancer is a rare type, considered of good prognosis.

Objective: To know the epidemiological and clinical characteristics of the population attended in the Hospital Juarez de Mexico, to know if they are alike to described worldwide and if the treatments proposed internationally are applicable for this hospitable center.

Methods: We performed a retrospective analysis.

[Study of 14 cases of breast cancer and pregnancy].

Introduction: Breast cancer is diagnosed in pregnant women during pregnancy or the first year after childbirth, and is the second leading cause of death among women of reproductive age. We don't know the frequency of this disease or the characteristics of the women affected at the Juarez Hospital of Mexico. This paper analyzed the cases of pregnant women diagnosed with breast cancer treated in the Oncology Department over a period of 10 years (1990-2000).

[Initial experience in laparoscopic retroperitoneal lymphadenectomy for the management of nonseminomatous testicular cancer].

Background: Germ cell tumors of the testis represent 1% of all cancers in males. The mean age of occurrence is between 15 and 35 years. Early diagnosis and accuracy of staging are factors that have an impact in survival.