Publications by authors named "Francisco M Marco De La Calle"

Background: One of the main barriers to vaccination against SARS-CoV-2 is the fear of developing hypersensitivity reactions to any of its components. Although these reactions are very rare, it is necessary to establish an effective protocol to detect patients at risk of developing them. The aim of this study was to evaluate hypersensitivity reactions in vaccinated patients in order to allow or not to complete the vaccination protocol.

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SARS-CoV-2 is the virus that causes the disease called COVID-19, which has caused the worst pandemic of the century. Both, to know the immunological status of general population and to evaluate the efficacy of the vaccination process that is taking place around the world, serological tests represent a key tool. Classic serological tests, based on colorimetric techniques, such as ELISA or CLIA, continue to be the most widely used option.

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Introduction: Granulomatous-lymphocytic interstitial lung disease (GLILD) is one of the most serious non-infectious complications in patients with common variable immunodeficiency (CVID). Its diagnosis and treatment are challenging.

Objective: To analyse the characteristics of Hospital General Universitario de Alicante patients with CVID and GLILD.

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Article Synopsis
  • Polyethylene glycols (PEGs) and their derivatives, commonly found in various products, can trigger allergic reactions, including severe hypersensitivity reactions, despite generally being considered safe.
  • A case study describes a 29-year-old woman who experienced both local and systemic allergic reactions to multiple products containing PEG, ultimately diagnosed with IgE-mediated hypersensitivity to these compounds.
  • To help prevent allergic reactions, it is suggested that standardizing the terminology for PEGs in product labeling would aid in better identification and awareness among patients.
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