Publications by authors named "Francisco Linde"

Article Synopsis
  • The study focused on identifying factors that contribute to the failure of asthma treatment step-down in patients with moderate to severe asthma who were on a combination therapy of inhaled glucocorticoids and long-acting beta agonists.
  • Results showed that 41.7% of patients experienced step-down failure, with significant factors including older age, multiple comorbidities, severity of asthma, and a short duration of previous asthma control.
  • The conclusion emphasizes that successful step-down is more likely when patients have maintained asthma control for over 6 months, suggesting that careful consideration is needed before adjusting treatment.
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Introduction And Hypothesis: A 60-year-old woman presented with congenital bladder exstrophy, urinary incontinence since birth, and pelvic organ prolapse since the menopause at the age of 46 years.

Methods: The patient (gravida 2, para 2 by cesarean sections and tubal ligation) described an extensive past surgical history that included epispadias and neourethral procedures, anti-reflux surgery using the Lich-Grégoir technique, bilateral ureterosigmoidostomy achieving continence, uterine fixation after the Doléris operation, and neovaginal reconstruction. The physical examination revealed a fourth-degree enterocele with cervical elongation (POP-Q: Aa-2, Ba-2, C + 3, D + 4, gh:5, pb:2.

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Sleep apnea-hypopnea syndrome (SAHS) is characterized by recurrent episodes of hypoxia/reoxygenation, which seems to promote oxidative stress. SAHS patients experience increases in hypertension, obesity, and dyslipidemia, and the oxidative state has been related to the genesis of these disorders. The purpose of this study was to examine the changes in oxidative stress markers and metabolic parameters in S AHS patients after 1 month of treatment with continuous positive airway pressure (CPAP), in relation to their previous metabolic disorders.

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