Factors associated with first molar dental enamel defects: a multivariate epidemiological approach.

Purpose: The purpose of this study was to ascertain factors linked to developmental defects of tooth enamel (DDE) in first permanent molars.

Methods: A retrospective epidemiological case-control study was conducted with 48 cases and 149 controls. Dental examinations were performed on 8-year-old children in accordance with World Health Organization (WHO) guidelines.