Publications by authors named "Francisco Jose Martinez"
Vivax malaria is an infectious disease caused by Plasmodium vivax, a parasitic protozoan transmitted by female Anopheline mosquitoes. Historically, vivax malaria has often been regarded as a benign self-limiting infection due to the observation of low parasitemia in Duffy-positive patients in endemic transmission areas and the virtual absence of infections in Duffy-negative individuals in Sub Saharan Africa. However, the latest estimates show that the burden of the disease is not decreasing in many countries and cases of vivax infections in Duffy-negative individuals are increasingly reported throughout Africa.
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- The study aimed to evaluate the characteristics and outcomes of left-side endocarditis caused by gram-negative bacteria, revealing it as a rare condition impacting significantly ill patients.
- Among 961 endocarditis cases studied, only 24 (2.5%) were linked to gram-negative bacteria, with Escherichia coli and Pseudomonas aeruginosa being the most common pathogens, often affecting native valves in patients with pre-existing health issues.
- Complications such as renal failure, central nervous system involvement, and high mortality rates (41%) were noted, and while aminoglycosides were commonly used, they did not improve patient outcomes.
This paper proposes a multiclassification algorithm using multilayer perceptron neural network models. It tries to boost two conflicting main objectives of multiclassifiers: a high correct classification rate level and a high classification rate for each class. This last objective is not usually optimized in classification, but is considered here given the need to obtain high precision in each class in real problems.
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