Publications by authors named "Francisco Jose Forestiero"
Maintained activity in ankylosing spondylitis patients treated with TNFi and/or NSAID for at least 12 weeks: a cross-sectional study in Brazil.
Adv Rheumatol
October 2022
Background: The aim of this study was to evaluate disease activity among patients with axial spondyloarthritis (AS) treated with tumor necrosis factor inhibitors (TNFi) and/or nonsteroidal anti-inflammatory drugs (NSAIDs) for at least 12 weeks in private outpatient settings in Brazil.
Methods: This was a cross-sectional, real-world study conducted in 17 Brazilian private health care institutes. Patients were selected if diagnosed with AS or axial radiographic spondyloarthritis (AxSpA) and treated with NSAIDs or TNFi for at least 12 weeks within the last 26 weeks prior to enrollment.
Objectives: To explore asthma control in patients undergoing pharmacotherapy on studies in the last 20 years in Brazil. Asthma is a chronic airway inflammation disease with a high prevalence worldwide. Even with a variety of drug treatment improvements, attaining asthma control is challenging, since it should have a personalized approach.
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- Hidradenitis suppurativa (HS) is a chronic skin condition that severely affects patients' quality of life, prompting a need for effective treatments.
- A systematic review was conducted to evaluate current treatment options for HS, particularly those available in Brazil, analyzing 70 relevant articles with an emphasis on therapy effectiveness.
- Findings indicate that while topical therapies and lifestyle changes are beneficial for mild HS, more severe cases may respond better to biologic treatments like adalimumab and infliximab, which have shown good safety and tolerability.
Background: Age-related macular degeneration (AMD) is a disease that causes damage in the macular region of the retina, leading to irreversible blindness. This study aims to understand the profile and care of patients with AMD and its cost at the Brazilian public health system to identify AMD-care needs.
Methods: This is a retrospective observational study of AMD with real-world data from the Brazilian public healthcare system, using DATASUS claim databases.
The relationship of NAT2, CYP2E1 and GSTM1/GSTT1 polymorphisms with mild elevation of liver biomarkers was investigated in individuals under anti-tuberculosis drug therapy. Tuberculosis outpatients (18-70 y) with (n=59) and without (n=40) mild increase of liver enzymes (MILE) at two-month treatment were selected. Blood samples were obtained for DNA extraction and evaluation of serum markers of liver function.
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