Publications by authors named "Francisco Javier Prado Galbarro"

Objective: To evaluate the main outcomes of disease activity and their association with other measures of activity, damage, and quality of life in patients with idiopathic inflammatory myopathy (IIM) according to time since diagnosis and positivity to antisynthetase autoantibodies (ASAs).

Methods: Cross-sectional multicenter study within the Spanish Myo-Spain registry. Cases were classified as incident (≤ 12 months since diagnosis) and prevalent.

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The poor prognosis of infections associated with multidrug-resistant can be attributed to several conditions of the patient and virulence factors of the pathogen, such as the type III secretion system (T3SS), which presents the ability to inject four effectors into the host cell: ExoS, ExoT, ExoU and ExoY. The aim of this study was to analyze the distribution of genes through multiplex polymerase chain reaction in strains isolated from patients at a third-level pediatric hospital and their relationships with clinical variables, e.g.

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  • Atypical bacterial pathogens can cause significant lung damage, but current diagnostic tests are not completely reliable, prompting the use of molecular techniques for detection.
  • This study aimed to assess the presence of these atypical bacteria in paediatric patients by analyzing 609 clinical samples from March 2021 to February 2024.
  • Results showed that 22.82% of patients had atypical organisms, with higher prevalence in neonates, and the presence of these bacteria tends to rise during warmer months; factors like prematurity and low weight were linked to respiratory distress syndrome (RDS).
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Speed limits are an evidence-based intervention to prevent traffic collisions and deaths, yet their impact on air pollution in cities is understudied. The objective of this study was to investigate the association between lower speed limits and air pollution. We leverage the introduction of a new road safety policy in Mexico City in December 2015 which lowered speed limits, increased fines, and installed speed radars to enforce compliance.

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Background: Non-medical use of psychoactive medication is a public health problem. Studies in other contexts indicate that individual sociodemographic characteristics are associated with non-medical use, but these associations have not been assessed in the Mexican context.

Objectives: To estimate the prevalence non-medical and medical use of psychoactive medication among Mexican adolescents and adults' medication users and to estimate the associations between sociodemographic characteristics and non-medical use of psychoactive medication, using data from a nationally representative sample.

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One of the most critical time periods in childhood is from birth to five years of age. Children exposed to alcohol and/or tobacco via family members and neighborhood are at risk for childhood developmental delays. This study evaluated the association of early childhood development with the prevalence of alcohol consumption and tobacco use in Mexican municipalities.

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Dysbiosis plays an important role in the development of bacterial infections in the gastric mucosa, particularly . The international guidelines for the treatment of infections suggest standard triple therapy (STT). Nevertheless, because of the increasing resistance rates to clarithromycin, metronidazole has been widely considered in several countries.

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  • A study examined how multimorbidity (the presence of multiple chronic diseases) and various socioeconomic and behavioral factors affect mortality risk in individuals aged 50 and older in Mexico.
  • Analysis of over 7,000 participants revealed high prevalence of conditions like chronic pain and hypertension, with socioeconomic and functional indicators strongly linked to increased death risk, especially among different age groups.
  • Findings suggest that addressing the complexities of multimorbidity and tailored care strategies can help reduce premature death across different age groups.
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Anti-inflammatory and analgesic medications (AAMs) are widely used in Mexico and the rest of the world. Their excessive acquisition can lead to waste, representing an unnecessary expense for families and the public health system. The aim of this study was to estimate the economic cost of the waste of unused AAMs collected by the National System for the Collection of Residues of Containers and Medications (SINGREM, the acronym in Spanish) in Mexico City during 2019.

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Background: Latin America and the Caribbean (LAC) is one of the most urbanized and violent regions worldwide. Homicides in youth (15-24 years old, yo) and young adults (25-39yo) are an especially pressing public health problem. Yet there is little research on how city characteristics relate to homicide rates in youth and young adults.

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Background: During the Covid-19 pandemic, children and adolescents faced poverty, potentially dying from preventable causes, or missing out essential vaccines. The aim of this study was to assess potential environmental and individual factors associated to COVID-19 mortality in children and adolescents in Mexico.

Methods: This cross-sectional study analysed the official data of 131,001 children under 10 years of age and adolescents between 10 and 19 years of age with COVID-19 disease, in Mexico.

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Background: Childhood is considered the most important phase of human development; within it the period from birth to 5 years of age is particularly critical, given the speed at which changes occur. The context where children live can influence early childhood developmnent (ECD) by providing or limiting opportunities to learn, play and establish social interactions. This study explored the associations between characteristics of the urban environment and ECD in 2,194 children aged 36 to 59 months living in urban municipalities in Mexico.

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  • The study aimed to estimate the prevalence and characteristics of axial osteoarthritis (OA) in Spain, focusing on people aged 40 and older.
  • Using a cross-sectional population-based approach, researchers found that the prevalence of non-exclusive axial OA (NEA-OA) was about 19.17%, increasing with age and body mass index, and was more common in women.
  • The findings highlight socio-demographic, anthropometric, and lifestyle factors associated with axial OA, marking it as the first study of its kind in Europe.
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  • * The study used data from national surveys in Mexico to investigate the link between early childhood development (ECD) and the prevalence of psychoactive substance use at the municipal level, revealing a connection between inadequate ECD and illegal drug use.
  • * Specifically, poor socio-emotional development was associated with an increased likelihood of illegal drug use, highlighting the need for effective interventions to prevent drug abuse and support early childhood development.
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Little is known about the potential impact of climate change on food systems and diet. We aimed to estimate the association of changes in rainfall and temperatures with consumption of unprocessed and processed foods among residents of Mexican cities by climate region. We analyzed 3,312 participants of the 2012 Mexican National Health and Nutrition Survey with dietary intake and sociodemographic information linked to historical rainfall and temperature data collected by the Mexican National Weather Service.

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Unlabelled: The health, economic, and social impact of COVID-19 has been significant across the world. Our objective was to evaluate the association between air pollution (through NO and PM levels) and COVID-19 mortality in Spanish provinces from February 3, 2020, to July 14, 2020, adjusting for climatic parameters. An observational and ecological study was conducted with information extracted from Datadista repository (Datadista, 2020).

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  • Emergency services (ES) are a vital part of modern healthcare systems, and this study aimed to explore how sociodemographic and clinical factors influence their usage among different populations in Spain.
  • The study analyzed data from the 2017 National Health Survey of Spain, focusing on three groups: young individuals (15-24), the elderly (75+ with multiple health issues), and the general population, employing descriptive analyses and logistic regression models.
  • Findings revealed that elderly individuals with multiple pathologies used ES the most (41.1%), while young people tended to seek help at private centers, with significant factors affecting ES usage including gender, social class, and health conditions.
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  • The study examined tobacco use and control policies in Latin America before and after the FCTC ratification in 2003, utilizing WHO reports and Global Youth Tobacco Survey data from six countries and numerous cities.
  • All countries showed improvements in tobacco control policies, but Mexico and Peru showed the least progress; notably, adolescents experienced reduced tobacco use and better education but less change in exposure to secondhand smoke outside the home.
  • The results highlighted significant variation in tobacco exposure among adolescents across different cities within the same countries, indicating inconsistent implementation of policies.
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Objectives: To examine the factors associated with satisfaction with healthcare services provided to patients with diabetes, hypertension, and/or dyslipidemia in the Mexican population.

Methods: In a cross-sectional, retrospective study, we used data from the 2016 Half-Way National Health and Nutrition Survey in Mexico (ENSANUT MC 2016). This contained self-reported information about patient satisfaction and use of healthcare services by 2529 adults.

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Objectives.: To estimate satisfaction with the healthcare received at facilities of the Ministry of Health (MINSA) of Peru and determine its associated factors in Peruvian adults.

Materials And Methods.

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Background: Mexico approved mandatory nutrient-based standards for foods sold in schools in 2011. The aim of this study was to analyse the association between compliance with nutrition standards for foods sold in schools and children's school snacks.

Methods: Data came from three surveys representative of Mexican elementary schools in 13 states and their students (2012, 2013 and 2015); n = 645 children from N = 99 different schools.

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Objectives: . To estimate out-of-pocket spending on health (GBS) and identify its associated factors in Peruvian older adults.

Materials And Methods.

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Associations between HLA class I alleles and HIV progression in populations exhibiting Amerindian and Caucasian genetic admixture remain understudied. Using univariable and multivariable analyses we evaluated HLA associations with five HIV clinical parameters in 3,213 HIV clade B-infected, ART-naïve individuals from Mexico and Central America (MEX/CAM cohort). A Canadian cohort (HOMER, n = 1622) was used for comparison.

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Seed oils from oleaginous plants are rich in fatty acids (FAs) that play important roles in the health of the consumers. Recent studies indicate that FA also can play an important role in communication and regulation of virulence in bacteria. Nevertheless, evidence demonstrating protection against bacterial infections mediated by their quorum sensing inhibition (QSI) activity is scarce.

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Objective: Heart failure (HF) is an important public health problem due to its increasing prevalence, and the decompensation associated with hospital admission represents an increased risk of death. The objective of this study was to compare several methods to model the variable hospitalizations and to determine the effect of factors associated with hospital admissions in incident cases of HF.

Methods: Study of a retrospective cohort of patients with information extracted from electronic medical records of PC was performed.

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