Publications by authors named "Francisco Javier Coves-Orts"

Background And Objectives: In the management of non-ST-segment elevation acute coronary syndromes (NSTE-ACS), several studies have shown a reduction in mortality with the use of an invasive strategy in high-risk patients, including diabetic patients. Paradoxically, other studies have shown an under-utilization of this invasive strategy in these patients. The aim of this study is to determine the characteristics of patients managed conservatively and identify determinants of the use of invasive or conservative strategy.

View Article and Find Full Text PDF

Aims: Several reports have suggested that nitrates limit acute ischaemic damage by a mechanism similar to preconditioning. This study aims to evaluate the effect of chronic oral nitrates on the clinical presentation and short-term outcomes of patients admitted with acute coronary syndrome (ACS).

Methods: A retrospective cohort study was conducted in patients with ACS admitted to 62 acute care units from 2010 to 2011.

View Article and Find Full Text PDF

Objectives: To evaluate the accuracy of B-type natriuretic peptide levels (BNP) in the diagnosis of heart failure and left ventricular dysfunction.

Data Sources: Electronic search in Medline, Embase, Cochrane Library and Medion database, and hand search of reference lists.

Review Methods: We have included published studies on the accuracy of BNP which had both sufficient information to construct the 2x2 diagnostic cross table and an appropriate spectrum of patients.

View Article and Find Full Text PDF

Objective: To report a probable interaction between meropenem and valproic acid that resulted in the development of epileptic seizures.

Case Summary: A 21-year-old woman presented to our emergency department because of a new-onset, generalized tonic-clonic seizure and was admitted to the intensive care unit. Treatment with valproic acid 1000 mg as a continuous intravenous infusion over 24 hours was initiated.

View Article and Find Full Text PDF