Lichen sclerosus (LS) is a chronic inflammatory disorder that predominantly affects the genital region of postmenopausal women, often resulting in significant morbidity due to pruritus and pain. Extragenital manifestations are rare and can present a diagnostic challenge. We report a case of a 65-year-old female presenting with white papules and plaques, some with a cribriform appearance, in an acral distribution.
View Article and Find Full Text PDFAcute-on-chronic liver failure is a syndrome associated with a high short-term mortality rate. Severe systemic inflammation and single- and multiple-organ failure are a hallmark of this syndrome, with pro-inflammatory precipitating events occurring in the liver or extrahepatic regions. We report a case of a 69-year-old man with a previous diagnosis of alcohol-induced liver cirrhosis who presented with a poorly defined, erythematous-purplish, and edematous plaque with multiple hemorrhagic blisters over the left leg, one day after receiving a spider bite.
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