Publications by authors named "Francisco J Anglada Curado"
PSA is the most widely used diagnosticand prognostic biomarker in prostate cancer (PCa).However, its lack of specificity has generated the needto search for new complementary markers. In thisscenario, blood plasma constitutes one of the sourcesof search for new markers, which have been tried tobe combined with PSA and other clinical variables inorder to develop tests that increase their diagnosticspecificity.
View Article and Find Full Text PDFDoes Adding Standard Systematic Biopsy to Targeted Prostate Biopsy in PI-RADS 3 to 5 Lesions Enhance the Detection of Clinically Significant Prostate Cancer? Should All Patients with PI-RADS 3 Undergo Targeted Biopsy?
Diagnostics (Basel)
July 2021
Article Synopsis
- - The study aimed to evaluate the added value of standard biopsy alongside targeted biopsy for cases with suspicious mp-MRI results, particularly analyzing when to skip biopsying PI-RADS 3 lesions.
- - Data from 483 biopsies revealed that while standard biopsy improved detection rates of clinically significant prostate cancer (csPCa) in specific groups, it was less effective for PI-RADS-5 lesions and in patients with a prior negative biopsy.
- - Conclusions indicate that standard biopsy can likely be avoided for patients with anterior lesions and PI-RADS-5 lesions, while targeted biopsy for PI-RADS-3 lesions is more effective in specific patient categories, particularly biopsy-naïve individuals.
Objectives: To compare low versus high frequency for lithotripsy in the management of distal ureteral calculi.
Methods: A total of 154 patients with radio-opaque calculi (0.5-1 cm diameter) in the distal ureter were randomized to be given either lithotripsy at 80 or 60 pulses per min (high frequency or low frequency groups, respectively).
Renal carcinoma may develop metachronous distant metastases without evidence of regional or local disease recurrence. These lesions may be misdiagnosed because of its benign-like appearance and lack of evidence of other disease spread.
View Article and Find Full Text PDFIncidence of renal carcinoma, one of the most fatal solid neoplasms, has steadily increased in Western society. Moreover, these tumors are being increasingly detected in their early stages. As with most cancers, the underlying causes of the disease remain unknown.
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