Publications by authors named "Francisco Hernandez Vicente"
A real-world evidence study of nabiximols in multiple sclerosis patients with resistant spasticity: Analysis in relation to the newly described 'spasticity-plus syndrome'.
Francesco Patti Clara Grazia Chisari Óscar Fernández Jorge Sarroca Elena Ferrer-Picón Francisco Hernández Vicente
Eur J Neurol
September 2022
Background And Purpose: Nabiximols is a therapeutic option for patients with multiple sclerosis (MS) spasticity whose symptoms are poorly controlled by conventional oral first-line medications. This study aimed to assess the relationship between changes in spasticity severity (measured on the 0-10 numeric rating scale [NRS]) and the presence of associated symptoms in patients treated with nabiximols, and to investigate the presence of the newly described 'spasticity-plus syndrome'.
Methods: We analyzed real-world data from the Italian Medicines Agency e-Registry on 1138 patients with MS spasticity who began treatment with nabiximols.
Article Synopsis
- Acne vulgaris affects many people, particularly on the face, chest, and back, but most research has focused on facial acne, with limited treatments for truncal acne.
- Sarecycline, a new oral antibiotic, shows promise as a safe and effective treatment, proven in phase-3 studies for moderate to severe acne.
- Analysis of two phase-3 studies revealed significant improvements in acne on the chest and back after 3, 6, and 12 weeks of sarecycline treatment compared to a placebo.