Publications by authors named "Francisco Erasmo de Oliveira"

Adipose tissue dysfunction influences the development of dyslipidemias associated with obesity, however, the mechanisms are still unclear. In this sense, the literature highlights the role of copper in cholesterol synthesis, contributing to the increase in concentrations of this lipid fraction and consequently to the manifestation of dyslipidemia. The objective of the study was to investigate the relationship between copper parameters and lipid profile markers in women with obesity.

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Some studies have demonstrated the involvement of high concentrations of copper in the manifestation of insulin resistance in individuals with obesity. The objective of this study was to evaluate the copper nutritional status and its relationship with parameters of glycemic control in women with obesity. An observational case-control clinical study involving 203 women aged between 20 and 50 years, divided into two groups: obese (n = 84) and eutrophic (n = 119).

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Studies have shown that deficiencies in magnesium, selenium, and zinc in individuals with obesity compromise the endogenous antioxidant defense system. This study aimed to evaluate the impact of mineral deficiency on enzymatic antioxidant defense in women with obesity. The study involved 63 women with obesity (BMI ≥ 35 kg/m) and 77 eutrophic women (BMI between 18.

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Article Synopsis
  • * Findings revealed that obese women had lower dietary intake and plasma concentrations of these minerals, along with higher urinary levels, regardless of their metabolic health status.
  • * The research indicates a significant correlation between deficiencies in these minerals and obesity-related metabolic issues, such as dyslipidemia and imbalances in redox status.
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Low-grade chronic inflammation is one of the main disorders that characterize adipose tissue dysfunction in obesity and is an important element in the pathogenesis of several comorbidities. In this context, selenium is an essential micronutrient that exerts important anti-inflammatory functions, and the role of selenium in controlling inflammation associated with obesity is not well defined. Thus, this study aimed to evaluate the relationship between markers of the nutritional status of selenium and low-grade chronic inflammation in obese women.

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Obesity is characterized by changes in the metabolism of zinc and thyroid hormones. Studies have also shown the role of zinc in the function and metabolism of thyroid. The present study aimed to evaluate the relationship between serum concentrations of thyroid hormones, dietary zinc intake and zinc distribution in obese women.

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Article Synopsis
  • The study investigates how cortisol affects zinc metabolism in morbidly obese women compared to normal weight controls.
  • It involved 80 women, with findings showing lower plasma zinc levels and higher urinary zinc excretion in the obese group.
  • Despite differences in zinc concentration, cortisol levels did not significantly correlate with zinc metrics, indicating cortisol may not influence zinc metabolism.
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