Objective: To evaluate the effect of tamoxifen in the lipidic and renal profile in diabetic and control rats.
Methods: 40 female Wistar rats had been used (180-220g corporal weight), divided randomly in 4 groups: C (n = 10, received vehicle), T (n = 10, treated with tamoxifen, 0.3mg/kg/day), D (n = 10, diabetic induced by streptozotocin, 45mg/Kg) and DT (n = 10, diabetic treated with tamoxifen).