Publications by authors named "Francisco Bravo Puccio"
Objective: Atopic dermatitis is a chronic, systemic, relapsing disease with dermatological manifestations, which imposes a high burden on patients, families and the health care system and has a high psychological, social, and economic impact and on the quality of life of patients. It mainly affects the pediatric population and, to a lesser extent, the adult population. The clinical presentation varies according to the age and evolution of the disease, and currently there are multiple pharmacological and non-pharmacological therapies available for the symptomatic management of patients.
View Article and Find Full Text PDFKaposi's sarcoma (KS) is the most frequent cancer in people living with HIV. Research on this condition is scarce in the region, therefore, this article aimed to describe the demographic, clinical and therapeutic characteristics of patients with HIV who developed KS at the Cayetano Heredia Hospital between 2000 and 2018. A total of 129 KS cases were identified, with a median age of 33 years, predominantly males with 92% (119/129), and mostly men who have sex with men (MSM).
View Article and Find Full Text PDFMultisystemic tuberculosis with skin involvement in a patient with compromised cellular immunity suggestive of primary immunodeficiency.
JAAD Case Rep
December 2022
Article Synopsis
- The Epstein-Barr virus (EBV) is a highly prevalent DNA virus that affects about 90% of people and can lead to various skin-related diseases, including certain lymphomas and other conditions associated with immune responses.
- EBV can cause a range of skin manifestations, such as infectious mononucleosis and severe allergies, and is more common in specific regions like South and Central America and parts of Asia.
- The study involves a comprehensive review of both the clinical and histopathological features of skin disorders linked to EBV and the human T-lymphotropic virus type-1, which is also associated with certain types of leukemia and skin conditions.
The oncogenic role of viruses in cutaneous neoplasms has been known by humankind for more than a century, when the origin of the common wart, or verruca vulgaris, was attributed to the human papilloma virus (HPV). Currently, virus-induced cutaneous neoplasms may be grouped into solid tumors and lymphoproliferative disorders. HPV, from which various serotypes are now known, each being linked to a specific neoplasm, the human herpes virus type 8 producing Kaposi sarcoma, and the Merkel cell polyomavirus, highlight among the first group.
View Article and Find Full Text PDFContext: Acral lentiginous melanoma is the most prevalent clinical presentation of melanoma in ethnic groups other than whites and also occurs in significant numbers in North America and Europe. Despite a clear-cut clinical picture, histologic findings seen in partial biopsies may be too subtle and deceive pathologists dealing with such cases.
Objectives: To make pathologists aware of the histologic findings during early phases of acral lentiginous melanoma (including the in situ phase), to compare those findings with what is seen in acral junctional nevus, and to highlight their similarities and differences.