Publications by authors named "Francisco Beraldi de Magalhaes"
Article Synopsis
- - The study focuses on analyzing tuberculosis incidence in the 399 municipalities of Paraná, Brazil, between 2018 and 2022, using ecological methods and various statistical models to identify patterns and factors influencing the disease.
- - Findings indicate that high-risk areas for tuberculosis are primarily located in the coastal/port, north, and northeast regions of Paraná, with factors such as municipal development index, environmental sanitation issues, and income inequality positively correlating with higher incidence rates.
- - The research highlights a paradox where tuberculosis clusters exist in regions with higher development indices but significant socioeconomic disparities, suggesting that income inequality contributes to ongoing tuberculosis challenges even in relatively developed areas.
Immunoassays are practical and cost-effective approaches suitable for large-scale tuberculosis (TB) screening. This study identified new peptide mimotopes of Mycobacterium tuberculosis and applied them in the serodiagnosis of TB. Thereby, linear (X, XCX) and constrained (LX-4 and LX-8) phage display peptide libraries were screened with purified Immunoglobulin G antibodies from TB-positive patients, and eight mimotopes were selected.
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