Methodological Optimization of Supercritical Fluid Extraction of Valuable Bioactive Compounds from the Acidophilic Microalga .

Microalgae grow in diverse environments and possess a great biotechnological potential as they contain useful bioactive compounds. These bioactive compounds can be obtained by selective and energy-efficient extraction methods. Various industries are using the supercritical fluid extraction (SFE) method to extract these valuable bioactive compounds.

Supercritical Fluid Extraction of Fucoxanthin from the Diatom and Biogas Production through Anaerobic Digestion.

is the marine diatom best known for high-value compounds that are useful in aquaculture and food area. In this study, fucoxanthin was first extracted from the diatom using supercritical fluid extraction (SFE) and then using the extracted diatom-like substrate to produce bioenergy through anaerobic digestion (AD) processes. Factors such as temperature (30 °C and 50 °C), pressure (20, 30, and 40 MPa), and ethanol (co-solvent concentration from 10% to 50% ) were optimized for improving the yield, purity, and recovery of fucoxanthin extracted using SFE.

Effect of Drying Methods on Lutein Content and Recovery by Supercritical Extraction from the Microalga sp. (MCH35) Cultivated in the Arid North of Chile.

In this study, we determined the effect of drying on extraction kinetics, yield, and lutein content and recovery of the microalga sp. (MCH35) using the supercritical fluid extraction (SFE) process. The strain was cultivated in an open-raceways reactor in the presence of seawater culture media and arid outdoor conditions in the north of Chile.

Non- Variants Detected in a High-Risk Chilean Cohort With a History of Breast and/or Ovarian Cancer.

Methods: Data were retrospectively collected from the registry of the High-Risk Breast and Ovarian Cancer Program at Clínica Las Condes, Santiago, Chile. Data captured included index case diagnosis, ancestry, family history, and genetic test results.

Results: Three hundred fifteen individuals underwent genetic testing during the study period.