Publications by authors named "Francisca Muyembe-Mawete"
Background: The Democratic Republic of the Congo has had 15 Ebola virus disease (EVD) outbreaks, from 1976 to 2023. On June 1, 2020, the Democratic Republic of the Congo declared an outbreak of EVD in the western Équateur Province (11th outbreak), proximal to the 2018 Tumba and Bikoro outbreak and concurrent with an outbreak in the eastern Nord Kivu Province. In this Article, we assessed whether the 11th outbreak was genetically related to previous or concurrent EVD outbreaks and connected available epidemiological and genetic data to identify sources of possible zoonotic spillover, uncover additional unreported cases of nosocomial transmission, and provide a deeper investigation into the 11th outbreak.
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- Distinct SARS-CoV-2 lineage B.1.620 was identified in Lithuania, featuring multiple mutations in the spike protein commonly found in concerning variants like E484K and S477N.
- The study highlights the lineage's potential resistance to neutralizing antibodies and documents local instances of transmission in Europe, particularly in Lithuania.
- Evidence suggests that B.1.620 likely originated in Central Africa, supported by advanced phylogeographic methods and travel history data from infected individuals.