Publications by authors named "Francisca Bass"
Am J Hematol
November 2024
Article Synopsis
- Autologous hematopoietic cell transplantation (AHCT) is an effective treatment for multiple myeloma, with real-world data collected from 61,725 patients revealing median overall survival of 90.2 months and median progression-free survival of 36.5 months.*
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- Cumulative relapse incidence and non-relapse mortality rates at 24 months were found to be 33% and 2.5% respectively, with better outcomes linked to factors like younger age, certain disease subtypes, and high performance status.*
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- Global variations were observed in patient outcomes based on registry data, influenced by differences in patient characteristics, use of maintenance treatments, and macroeconomic factors, highlighting the safety and effectiveness of AH
Rev Med Chil
September 2021
Article Synopsis
- Before tyrosine kinase inhibitors (TKIs) were introduced, patients with Philadelphia-positive Acute Lymphoblastic Leukemia (Ph+ALL) had poor outcomes; the combination of TKIs with intense chemotherapy has significantly improved these results.
- A study conducted on 35 patients at a public hospital in Santiago, Chile, between 2010 and 2019 showed a 97% complete response rate, and 61% had no measurable residual disease (MRD) during follow-up.
- While the overall survival and event-free survival rates at three years were 52% and 34% respectively, achieving MRD negativity before three months did not significantly improve these outcomes, suggesting the combined treatment is an effective option for Ph+
