The aim of this study was to screen the chemical components of leaves and assess their therapeutic attributes with regard to their antioxidant, antibacterial, and antidiabetic activities. The antidiabetic effects were explored to determine the α-amylase and α-glucosidase inhibitory potential of the leaf extract. To identify the active antidiabetic drugs from the extracts, the GC-MS-screened molecules were docked with diabetes-related proteins using the glide module in the Schrodinger Tool.
View Article and Find Full Text PDFEthnopharmacological Relevance: Traditional medicine remained as the most affordable and easily accessible source of treatment for many ailments. The Malayali tribes living in the Kolli hills region of Eastern Ghats of Tamil Nadu has long history of ethnomedicinal knowledge has been remained unexplored hither to. Hence, this study was initiated with an aim to record the ethnomedicinal plants of Malayali tribes and to document and analyse the local knowledge on phytotherapy before environmental and cultural changes deplete the resources.
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