Publications by authors named "Francis Tetteh"

Article Synopsis
  • - Previous studies in Ghana found low prevalence of MRSA but noted the dominant presence of ST152 methicillin-susceptible strains; however, a recent investigation using whole genome sequencing revealed significant levels of methicillin resistance (38%) and virulence factors (65% for PVL) in clinical isolates from various infections.
  • - A majority (74%) of the MRSA strains belonged to the ST152 clone, with other MRSA clones detected, while methicillin-susceptible strains included ST3249 and others; resistance genes were prevalent, especially those against common antibiotics like tetracyclines and phenicols.
  • - Phylogenetic analysis indicates a trend toward ST152 MRSA becoming the dominant strain over the
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Introduction: Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae are pathogens of significant public health interest for which new antibiotics are urgently needed.

Aim: To determine the prevalence of ESBLs in E. coli and K.

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Infectious diseases continue to be the leading cause of morbidity and mortality, and a formidable obstacle to the development and well-being of people worldwide. Viruses account for more than half of infectious disease outbreaks that have plagued the world. The past century (1918/19-2019/20) has witnessed some of the worst viral disease outbreaks the world has recorded, with overwhelming impact especially in low- and middle-income countries (LMIC).

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In this study, we described the bacterial profile, antibiotic resistance pattern, and laboratory result turnaround time (TAT) in neonates with suspected sepsis from a tertiary-level, military hospital in Accra, Ghana (2017-2020). This was a cross-sectional study using secondary data from electronic medical records. Of 471 neonates clinically diagnosed with suspected sepsis in whom blood samples were collected, the median TAT from culture request to report was three days for neonates who were culture-positive and five days for neonates who were culture-negative.

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Background: Accreditation is important for all medical laboratories, particularly public health laboratories in developing countries. Several laboratories in Ghana implemented the requirements of the International Organization for Standardization (ISO) 15189 but were unable to proceed to accreditation. This article describes the challenges faced by the Pathology Division Laboratory of the 37 Military Hospital, Accra, Ghana, during the acquisition of ISO 15189 accreditation and suggests solutions for a better approach.

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Declining soil fertility among smallholder farmers in the Savannah zones of Ghana, among other issues, is triggered by continuous cultivation, low fertilizer use and low soil organic matter content. The area is faced with insufficient domestic production, food insecurity and poverty, all of which constitute major constraints to national development. Continuous cultivation leads to low soil organic matter levels.

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