Publications by authors named "Francis Tatong Ngouafong"
Article Synopsis
- The paper identifies eight new triterpenoid saponins, including afzeliioside A and several pairs of acetylated regioisomers (B/C, D/E) along with afzeliiosides F-H and the known impatiprin C, all isolated from a specific liana species.
- Their structures were determined through advanced techniques like NMR and mass spectrometry, supported by comparative spectral analysis with similar compounds.
- The cytotoxic activity of these compounds was evaluated against CAL-27 oral squamous carcinoma cells, revealing that only one compound showed moderate activity (EC = 36.0 μg/mL).
Phytochemical investigation of the methanol extracts from the leaves and bark of resulted in the isolation of one new flavone -glycoside: apigenin-8--[6''-feruloyl]---glucopyranoside] (), together with sixteen known compounds including quercetin-3----rhamnoside (), vitexin (), isovitexin (), quercetin-3----glucopyranoside (), quercetin-3----arabinopyranoside (), quercetin (), kaempferol (), methyl inositol (), sucrose (), betulinic acid (), vanillic acid (), stigmastane-3,6-diol (), aurantiamide acetate (), robinetinidol (), catechin () and epicatechin (). The structures of these compounds were established on the basis of their spectroscopic (1 D and 2 D NMR) and mass spectrometric (ESI-TOF-MS) data. The methanol extracts, fractions and some of the isolated compounds were screened for their antimicrobial properties against five microbial strains.
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