Publications by authors named "Francis Phan"

Background: Safe and effective management of venous vascular access is a key component of electrophysiology (EP) procedures. Recently, the Z-stitch method has been developed for effective venous hemostasis. However, the standard postprocedure protocol often includes prolonged bed rest, which may affect patient satisfaction.

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Article Synopsis
  • Paroxysmal atrial fibrillation (pAF) can develop into persistent atrial fibrillation (psAF), but some patients experience psAF without previous pAF, which might influence their response to direct current cardioversion (DCCV).
  • This study aimed to analyze how a history of pAF impacts recurrence rates post-DCCV in patients with their first psAF episode.
  • Findings showed that patients with primary psAF had longer AF survival times and less recurrence after DCCV compared to those with a history of pAF, suggesting that pAF patients may require more proactive rhythm control strategies.
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Background: Lead dwell time is the single strongest predictor of failure and complications in transvenous lead extraction.

Objectives: To report the success rate and complications of transvenous lead extractions with implant dwell time of at least 15 years.

Methods: Procedural and patient data were prospectively collected into a database.

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Background: The impact of lead fixation mechanism on extractability is poorly characterized.

Objective: We aimed to compare the technical difficulty of transvenous lead extraction (TLE) of active vs passive fixation right ventricular (RV) leads.

Methods: A total of 408 patients who underwent RV TLE by a single expert electrophysiologist at Oregon Health & Science University between October 2011 and June 2022 were identified and retrospectively analyzed; 331 (81%) had active fixation RV leads and 77 (19%) had passive fixation RV leads.

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Background—: Sex is a well-recognized risk factor for sudden cardiac death (SCD). We hypothesized that sex modifies the association of electrophysiological (EP) substrate with SCD.

Methods—: Participants from the Atherosclerosis Risk in Communities study with analyzable ECGs (n=14,725; age, 54.

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Background: Mechanisms of arrhythmogenicity in hypertrophic cardiomyopathy (HCM) are not well understood.

Objective: To characterize an electrophysiological substrate of HCM in comparison to ischemic cardiomyopathy (ICM), or healthy individuals.

Methods: We conducted a prospective case-control study.

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Background Race is an established risk factor for sudden cardiac death (SCD). We sought to determine whether the association of electrophysiological substrate with SCD varies between black and white individuals. Methods and Results Participants from the ARIC (Atherosclerosis Risk in Communities) study with analyzable ECGs (n=14 408; age, 54±6 years; 74% white) were included.

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Introduction: Microspheres fabricated from natural materials serve as a promising biodegradable and biocompatible carrier in a small volume for efficient cell delivery to the lesion of the injured neural tissue to generate biological functions. As the major component of extracellular matrix and due to its natural abundance within the body, collagen may be fabricated into microspheres and improve the ability of pre-seeded cells on the microspheres to encounter the hostile micro-environment in the lesion.

Methods: In this study, collagen microspheres were fabricated using the water-in-oil emulsion technique and cross-linked with 1-ethyl-3-(3-dimethylaminopropryl) carbodiimide.

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