Publications by authors named "Francis Osowik"
Article Synopsis
- In southeastern Ohio, the prevalence of diabetes is significantly higher than the national average, leading to increased levels of diabetes distress and major depressive disorder among patients.
- The study aimed to assess diabetes distress, clinically significant depressive symptoms, and their effects on A1c levels, self-care behaviors, and diabetes quality of life among local patients with diabetes.
- Researchers used various validated questionnaires to gather data from 325 participants, analyzing the relationships between depressive symptoms, diabetes distress, and overall diabetes management and quality of life.
Alcohol consumption is largely associated with alterations in the extracellular glutamate concentrations in several brain reward regions. We recently showed that glutamate transporter 1 (GLT-1) is downregulated following chronic exposure to ethanol for 5 weeks in alcohol-preferring (P) rats and that upregulation of the GLT-1 levels in nucleus accumbens and prefrontal cortex results, in part, in attenuating ethanol consumption. Cystine glutamate antiporter (xCT) is also downregulated after chronic ethanol exposure in P rats, and its upregulation could be valuable in attenuating ethanol drinking.
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