Publications by authors named "Francis Meignan"

Objectives: To describe the long-term effects of Hylan GF-20 viscosupplementation in patients with knee osteoarthritis and to identify factors predicting efficacy.

Methods: One hundred and fifty-five patients (80 women and 75 men; mean age, 69 years) with symptomatic knee osteoarthritis each received three intraarticular Hylan GF-20 injections. Effectiveness, safety, and satisfaction were evaluated 7-14 months later based on a physician's examination and a five-item questionnaire.

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Article Synopsis
  • A 49-year-old man with seropositive rheumatoid arthritis (RA) developed large, rapidly progressing geodes in his wrists, hands, and feet, which is atypical for such cases.
  • Despite the presence of these geodes, he experienced minimal joint destruction, maintained good functional ability, and showed only moderate signs of inflammation.
  • The unusual combination of large geodes and the patient's overall good condition highlights a rare occurrence in the progression of RA.
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