Publications by authors named "Francine Sumie Morikava"
Article Synopsis
- The study focused on creating and testing chlorhexidine:β-cyclodextrin (Chx:βCD) complexes for their antifungal properties.
- Physicochemical analysis showed that a 1:2 molar ratio of Chx:βCD was optimal for achieving antifungal activity against nine different fungal strains.
- When added to denture material, Chx:βCD demonstrated enhanced antifungal effectiveness, needing only 7.5% of Chx concentration to remain effective for 14 days, suggesting potential for new treatments for oral candidiasis and denture stomatitis.
Background: Nystatin (Nys) is a fungicidal drug commonly prescribed for candidiasis disease in several administration routes. However, Nys is a class IV drug, according to the Biopharmaceutical Classification System, that possesses limited bioavailability and is used for local activity.
Objective: This study developed and characterized nystatin:β-cyclodextrin (Nys:βCD) inclusion complexes and evaluated their activity against spp.
Objective: To evaluate the association of the consumption of healthy and cariogenic foods with the prevalence of untreated dental caries among preschool children.
Materials And Methods: A cross-sectional study was conducted with 427 5-year-old preschoolers. Caries was evaluated through a clinical examination using dmft index.