Publications by authors named "Francesco Vaiano"

Oxygen-ozone therapy has garnered increasing attention for its potential therapeutic applications, yet its widespread adoption is hindered by inconsistent protocols and a lack of standardized guidelines. Standardizing these protocols is essential to ensure the safety, efficacy, and reproducibility of treatments. Advanced training for physicians and caregivers is paramount, equipping them with evidence-based knowledge and practical expertise to administer this therapy effectively while avoiding unverified or misleading innovative approaches.

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  • * Two clinical studies demonstrated the effectiveness of ozone in treating infected post-surgical wounds and knee osteoarthritis, with notable reductions in infection and inflammation.
  • * The findings suggest that ozone therapy can enhance immune response, promote bacterial clearance, and alleviate symptoms in patients with specific conditions.
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  • * It operates on the principle of hormesis at low doses, promoting cell protection through the activation of the body's antioxidant systems and having anti-inflammatory effects.
  • * As a bioregulator, ozone enhances mitochondrial function and influences complex regulatory mechanisms in cells, making it a novel approach in pharmacology and medical treatments.
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Ozone major autohemotherapy is effective in reducing the symptoms of multiple sclerosis (MS) patients, but its effects on brain are still not clear. In this work, we have monitored the changes in the cerebrovascular pattern of MS patients and normal subjects during major ozone autohemotherapy by using near-infrared spectroscopy (NIRS) as functional and vascular technique. NIRS signals are analyzed using a combination of time, time-frequency analysis and nonlinear analysis of intrinsic mode function signals obtained from empirical mode decomposition technique.

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