Publications by authors named "Francesco Paolo Cappuccio"

Article Synopsis
  • The study investigates salt intake among adults in the 53 Member States of the WHO European Region, aiming to assess compliance with the WHO's recommendation of consuming less than 5 g of salt daily to lower cardiovascular disease (CVD) risk.
  • It systematically reviewed data from studies and surveys published between 2000 and 2022, discovering that 98% of the countries reported salt intake levels exceeding the WHO guidelines, with men generally consuming more salt than women.
  • The research highlights significant regional differences in salt intake, with Western and Northern Europe having lower averages compared to Eastern Europe and Central Asia, while also noting the variability in methods used to measure salt consumption, indicating potential underestimations in some cases.
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High sodium (salt) consumption is associated with an increased risk of developing non-communicable diseases. However, in most European countries, Portugal included, sodium intake is still high. This study aimed to assess the sodium content of school meals before and after the Eat Mediterranean (EM) intervention-a community-based program to identify and correct nutritional deviations through the implementation of new school menus and through schools' food handlers training.

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Cardiovascular disease, including stroke, heart failure and kidney disease, has been common in sub-Saharan Africa for many years, and rapid urbanization is causing an upsurge of ischaemic heart disease and metabolic disorders. At least two-thirds of cardiovascular deaths now occur in low- and middle-income countries, bringing a double burden of disease to poor and developing world economies. High blood pressure (or hypertension) is by far the commonest underlying risk factor for cardiovascular disease.

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Shared environmental factors may confer to spouses a similar risk for cardiovascular disease. We aimed at investigating in pairs the concordance in risk factors for cardiovascular disease and in global risk of cardiovascular events. In the framework of the IMMIDIET Project, married couples, recruited randomly from general practice, were studied.

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Genes of the renin-angiotensin-aldosterone system (RAAS) are natural candidates for sodium homeostasis and blood pressure regulation. To investigate the effect of a combination of polymorphisms of RAAS genes on renal sodium handling and blood pressure, 918 participants to the Olivetti Heart Study were genotyped for the following polymorphisms: I/D of angiotensin converting enzyme (ACE), M235T of angiotensinogen (AGT), A1166C of angiotensin II type-1 receptor (AT1R), and C-344T of aldosterone synthase (CYP11B2). The segmental renal sodium handling was evaluated by the fractional excretions of exogenous lithium (FE-Li), uric acid (FE-UA), and sodium (FE-Na).

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Background: The renin-angiotensin system is involved in adipocyte growth and differentiation and possibly in adipose tissue metabolism.

Objective: To investigate the association of polymorphism in the angiotensin-converting enzyme (ACE) I/D gene, angiotensinogen M235T gene, and angiotensin II type 1 receptor A1166C gene with body mass index, body fat pattern, and obesity-associated hypertension.

Design: Cross-sectional longitudinal study.

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