Publications by authors named "Francesco Mesquita"

Objective: To describe the evidence of Platelet Rich Plasma (PRP), Stem cells therapy (SCT) and Extracorporeal shockwave therapy (ESWL) for the treatment of Peyronies disease (PD), including information from the main urological society guidelines.

Materials And Methods: A literature review of PubMed articles published between 2000 and 2023 was conducted, utilizing keywords such as "Peyronie's Disease", "Penile curvature", "Platelet Rich Plasma", "Stem cells", and "Extracorporeal shockwave therapy". Only full-text articles in English were included, excluding case reports and opinions.

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Article Synopsis
  • The rising issue of microplastics (MPs), tiny particles less than 5 mm, poses serious risks to both the environment and human health, finding their way into food and drink.
  • A study aimed to investigate the presence of MPs in human penile tissue sampled from patients undergoing surgery for inflatable penile prosthetics, using advanced imaging techniques for analysis.
  • Results showed that MPs were detected in 80% of samples, with common types found being polyethylene terephthalate and polypropylene, prompting concerns about the impact of these pollutants on sexual health.
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Introduction: Obstructive azoospermia occurs when there is a blockage in the male reproductive tract, leading to a complete absence of sperm in the ejaculate. It constitutes around 40% of all cases of azoospermia (1, 2). Blockages in the male reproductive tract can arise from either congenital or acquired factors, affecting various segments such as the epididymis, vas deferens, and ejaculatory ducts (3).

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Article Synopsis
  • - The video provides a detailed tutorial on microsurgical reconstruction for obstructive azoospermia, specifically focusing on the procedure of connecting the vas deferens to the rete testis, aimed at aiding healthcare professionals in reproductive medicine.
  • - It utilizes advanced technology, like the ORBEYE 4K 3D Camera, to offer clear surgical footage while ensuring ethical standards by obtaining patient consent and reviewing medical histories.
  • - The findings suggest that this surgical method is an effective option for treating obstructive azoospermia, especially in cases with non-dilated epididymis tubules, contributing valuable insights to the field of reproductive medicine.
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Article Synopsis
  • A retrospective study assessed the effectiveness of low-dose prednisone as a treatment for men who experienced worsening semen parameters after vasovasostomy surgery, focusing on sperm concentration, motility, and total motile sperm count.
  • Eight patients who showed at least a 50% decline in these parameters were treated with 6 weeks of prednisone, leading to significant improvements in total motile sperm count (TMSC) with a median increase of 6 million and a 433% relative improvement.
  • No adverse effects were reported, indicating that low-dose prednisone could safely help restore fertility in these patients, but further research with larger groups is needed to confirm these findings and explore other treatment options.
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