Publications by authors named "Francesco Maria Animati"
The recently introduced concept of 'exposome' emphasizes the impact of non-traditional threats onto cardiovascular health. Among these, air pollutants - particularly fine particulate matter < 2.5 μm (PM2.
View Article and Find Full Text PDFAcetylsalicylic acid (ASA) represents a cornerstone of antiplatelet therapy for the treatment of atherosclerotic coronary artery disease (CAD). ASA is in fact indicated in case of an acute coronary syndrome or after a percutaneous coronary intervention with stent implantation. Aspirin hypersensitivity is frequently reported by patients, and this challenging situation requires a careful evaluation of the true nature of the presumed sensitivity and of its mechanisms, as well as to differentiate it from a more frequent (and more easily manageable) aspirin intolerance.
View Article and Find Full Text PDFArticle Synopsis
- Current guidelines for acute coronary syndrome (ACS) focus on clinical presentation but are shifting towards understanding the underlying pathophysiology, recognizing that plaque destabilization isn't the only cause.
- The use of intracoronary imaging and biomarkers is helping to identify different ACS types (endotypes), enabling personalized treatment plans and new therapy targets.
- A precision medicine approach for conditions like MYOCARDIAL INFARCTION with non-obstructive coronary arteries (MINOCA) is emphasized, aiming at optimizing diagnosis and treatment to reduce risks and improve outcomes for patients.
Background And Aims: Air pollution is emerging as an important risk factor for acute coronary syndrome (ACS). In this study, we investigated the association between short-term air pollution exposure and mechanisms of coronary plaque instability evaluated by optical coherence tomography (OCT) imaging in ACS patients.
Methods: Patients with ACS undergoing OCT imaging were retrospectively selected.