Publications by authors named "Francesco Dubini"

Antibiotic susceptibility testing of Helicobacter pylori isolates was performed by broth microdilution method with MegaCell RPMI-1640 Medium (SIGMA). Fifty five clinical isolates of H. pylori were tested against metronidazole, tinidazole, amoxicillin, and clarithromycin.

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Several in vitro studies with a new medical device (Myfungar) containing 0.5% of piroctone olamine (CAS 68890-66-4, octopirox) in a hydroxypropyl chitosan hydroalcoholic solution were performed. The chemical name of the active ingredient is 1-hydroxy-4-methyl-6 (2,4,4-trimethylpentyl)-2(1H)-pyridone; combination with 2-amino-ethanol (1:1).

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Article Synopsis
  • * Experimenting with mice, researchers found that injecting them with CpG oligonucleotides reduced TLR9 and led to fewer secretory granules in Paneth cells, indicating degranulation.
  • * The treatment with CpG oligonucleotides also improved the mice's resistance to infection by Salmonella typhimurium, highlighting the protective function of Paneth cells through TLR9.
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