Effect of Synthetic Vitreous Fiber Exposure on TMEM16A Channels in a Oocyte Model.

Many years ago, asbestos fibers were banned and replaced by synthetic vitreous fibers because of their carcinogenicity. However, the toxicity of the latter fibers is still under debate, especially when it concerns the early fiber interactions with biological cell membranes. Here, we aimed to investigate the effects of a synthetic vitreous fiber named FAV173 on the oocyte membrane, the cell model we have already used to characterize the effect of crocidolite asbestos fiber exposure.