Publications by authors named "Francesco Bencivenga"

Low-pathogenic human coronaviruses (HCoVs) infect the upper respiratory tract and cause mild, cold-like respiratory illness. Although several studies have shown evidence of the global distribution of HCoVs, information about their distribution in Italy are often focused only on hospitalized children and elderly with respiratory symptoms. In this study, a total of 916 swab samples collected during the first two SARS-CoV-2 pandemic waves in Abruzzo region (central Italy) was selected for molecular screening of low pathogenic HCoVs by real-time RT-PCR.

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Article Synopsis
  • - The study evaluated a SARS-CoV-2 mutant with a specific ten-amino acid deletion in the spike protein, comparing its effects to the original strain and two Delta variants using K18-hACE2 mice.
  • - Mice were monitored for weight loss, lethality, and clinical symptoms for 14 days after being infected, with various tests conducted to assess viral presence and immune response.
  • - Results showed that the mutant infection led to less viral shedding, reduced lung virulence, and milder lung damage, along with significantly lower levels of certain cytokines, indicating a less severe immune response.
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West Nile virus (WNV) and Usutu virus (USUV), two antigenically related flaviviruses co-circulating in Europe, can cause severe neurological disease in animals and humans. The immune response against USUV and WNV and their immunopathogenesis are still poorly investigated. Here we present results upon sequential infections of adult immunocompetent CD-1 and BALB/c mice primed with two different doses (high dose, HD or low dose, LD) of an USUV isolate and challenged with HD or LD of three different WNV isolates.

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Epstein-Barr virus (EBV) is a common herpesvirus that may cause asymptomatic infection or various diseases, such as mononucleosis, lymphoproliferative disorders and several cancers. Our objective was to estimate the prevalence of EBV among patients hospitalized in "Luigi Vanvitelli" University Hospital in the last 10 years. Our results showed that EBV seroprevalence in our geographical area was 65%.

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The objectives of this survey were to assess the knowledge, attitudes, and behaviors toward eating disorders among adolescents in Italy. The survey was undertaken between May and June 2017 among a random sample of 420 adolescents aged 14-20 years. Data were collected through a self-administered questionnaire.

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