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View Article and Find Full Text PDFRunx2 is a transcription factor involved in melanoma cell migration and proliferation. Here, we extended the analysis of Runt domain of Runx2 in melanoma cells to deepen understanding of the underlying mechanisms. By the CRISPR/Cas9 system we generated the Runt KO melanoma cells 3G8.
View Article and Find Full Text PDFMaximum annual daily precipitation is a fundamental hydrologic variable that does not attain asymptotic conditions. Thus the classical extreme value theory (i.e.
View Article and Find Full Text PDFMonitoring the snow pack is crucial for many stakeholders, whether for hydro-power optimization, water management or flood control. Traditional forecasting relies on regression methods, which often results in snow melt runoff predictions of low accuracy in non-average years. Existing ground-based real-time measurement systems do not cover enough physiographic variability and are mostly installed at low elevations.
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