Effects of selection and mutation on epidemiology of X-linked genetic diseases.

The epidemiology of X-linked recessive diseases, a class of genetic disorders, is modeled with a discrete-time, structured, non linear mathematical system. The model accounts for both de novo mutations (i.e.

Selection and mutation in X-linked recessive diseases epidemiological model.

To describe the epidemiology of X-linked recessive diseases we developed a discrete time, structured, non linear mathematical model. The model allows for de novo mutations (i.e.