Publications by authors named "Francesca Scaramuzzi"
Background/aim: To evaluate and stratify early cardiovascular risk of transsexuals who underwent pharmacological and/or surgical gender reassignment.
Methods: Fifty-six transsexuals were divided into two groups: group 1 - underwent gonadectomy (orchiectomy for transwomen and hystero-annessiectomy for transmen); group 2 - hormone replacement therapy alone. All participants underwent carotid artery intima-media thickness (C-IMT) and flow-mediated vasodilation (FMD) of brachial artery evaluations.
Article Synopsis
- - Several studies suggest a higher occurrence of metabolic syndrome (MetS) in people with psychiatric disorders and individuals receiving cross-sex hormone treatment for gender dysphoria (GD), but the specific prevalence of MetS in hormone-treated GD patients with psychiatric issues has not been explored before.
- - In this study involving 122 metabolically healthy GD patients over two years of hormonal treatment, changes were observed in MetS-related health parameters, with significant differences noted from their initial condition; notably, MetS developed in 14.8% and 17.2% of the sample after one and two years, respectively.
- - The findings reveal that those with concurrent psychiatric problems exhibited a much higher prevalence of MetS, with 50%