Publications by Francesca Saveria Amoroso

Publications by authors named "Francesca Saveria Amoroso"

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Involvement of the P2X7-NLRP3 axis in leukemic cell proliferation and death.

Erica Salaro Alessia Rambaldi Simonetta Falzoni Francesca Saveria Amoroso Alessia Franceschini

Sci Rep

May 2016

Lymphocyte growth and differentiation are modulated by extracellular nucleotides and P2 receptors. We previously showed that the P2X7 receptor (P2X7R or P2RX7) is overexpressed in circulating lymphocytes from chronic lymphocytic leukemia (CLL) patients. In the present study we investigated the P2X7R/NLRP3 inflammasome axis in lymphocytes from a cohort of 23 CLL patients.

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