Publications by authors named "Francesca S Fernando"
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Synopsis of recent research by authors named "Francesca S Fernando"
- Francesca S Fernando's research primarily investigates common molecular and cellular mechanisms involved in neurodegenerative diseases and neuroinflammation, focusing on the pathological features shared among various conditions such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis.
- Utilizing gene expression microarray technology, her studies have revealed critical insights into the gene expression alterations associated with neurodegenerative disorders, emphasizing pathways like abnormal protein deposition, cellular transport dysfunction, and mitochondrial deficits.
- Notably, her findings highlight the significance of oxidative stress and dopamine metabolism in Parkinson's disease, particularly implicating the gene ALDH1A1 in neuronal cell death, thereby advancing the understanding of neuronal cell fate in neurodegenerative processes.
