Evaluation of DNA methylation of inflammatory genes following treatment of chronic periodontitis: A pilot case-control study.

Objective: To evaluate the influence of periodontal therapy on DNA methylation in patients with chronic periodontitis as compared to healthy individuals.

Material And Methods: Twenty patients were enrolled into two groups: (i) 10 diagnosed as clinically healthy; and (ii) 10 diagnosed with chronic periodontitis. Clinical measures were recorded and gingival biopsies were harvested at baseline (both patient groups) and at 2 and 8 weeks post-baseline for diseased individuals.

Biofilm removal from implants supported restoration using different instruments: a 6-month comparative multicenter clinical study.

Objectives: The aim of this study was to compare the efficacy of different instruments on biofilm removal from implant supported restorations.

Materials And Methods: The study was designed as comparative multicenter clinical study including patients proceeding from the Milan, Naples, and Buenos Aires, with a peri-implant mucositis. Implants enrolled for the study were allocated in 4 groups and treated with ultrasonic scalers with plastic tips, with titanium curettes, with airflow with glycine powder, and with rubber cup and polishing paste, respectively.