Publications by authors named "Francesca Patria"
Article Synopsis
- Spinal Muscular Atrophy (SMA) is an inherited condition that leads to muscle weakness and respiratory issues due to the degeneration of spinal motor neurons, particularly affecting the intercostal muscles responsible for breathing.
- Children with SMA type 1 face a high risk of respiratory failure, often leading to serious outcomes without intervention, though modern therapies and assisted ventilation can improve survival rates.
- There's limited information on sleep disorders in SMA patients, and this review emphasizes the need for a comprehensive care approach that includes monitoring respiratory health and incorporating advancements in treatment to enhance quality of life.
The existence of common inflammatory biomarkers linking obesity and asthma in children has been hypothesized. Nevertheless, laboratory and clinical characteristics of children with obesity and asthma are still poorly defined. The primary aim of the present study is to investigate the lung function and the cytokine profile, in children with obesity and asthma.
View Article and Find Full Text PDFBackground: The aim of this case-control study was to analyse the clinical characteristics of children with recurrent community-acquired pneumonia (rCAP) affecting different lung areas (DLAs) and compare them with those of children who have never experienced CAP in order to contribute to identifying the best approach to such patients.
Methods: The study involved 146 children with ≥2 episodes of radiographically confirmed CAP in DLA in a single year (or ≥3 episodes in any time frame) with radiographic clearing of densities between occurrences, and 145 age- and gender-matched controls enrolled in Milan, Italy, between January 2009 and December 2012. The demographic and clinical characteristics of the cases and controls were compared, and a comparison was also made between the cases with rCAP (i.