Publications by authors named "Francesca Panzitta"
The imprints of domestication and breed development on the genomes of livestock likely differ from those of companion animals. A deep draft sequence assembly of shotgun reads from a single Hereford female and comparative sequences sampled from six additional breeds were used to develop probes to interrogate 37,470 single-nucleotide polymorphisms (SNPs) in 497 cattle from 19 geographically and biologically diverse breeds. These data show that cattle have undergone a rapid recent decrease in effective population size from a very large ancestral population, possibly due to bottlenecks associated with domestication, selection, and breed formation.
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- - The cattle genome was sequenced to enhance the understanding of ruminant biology and evolution, containing at least 22,000 genes with 14,345 orthologs shared across seven mammal species.
- - Certain regions in the cattle genome have a higher density of segmental duplications, indicating unique evolutionary changes, particularly in genes linked to lactation and immune responses.
- - This genome sequence serves as a valuable resource for studying mammalian evolution and improving livestock genetics, which can lead to better milk and meat production.
Online resources for the bovine genome analysis are provided at the most important Web sites. Nonetheless, retrieval of single-nucleotide polymorphism (SNP)-related information is not always easy when searches must focus on complementary features. In this work, we present the Bovine SNP Retriever: a user-friendly tool for bovine SNP retrieval that also facilities the retrieval of SNP-related information within user-selected quantitative traits loci regions and reverse electronic polymerase chain reaction analysis on the bovine genome.
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